Abstract : Background: Spinal anesthesia is an attractive choice for ambulatory surgery of the lower abdomen and
lower limbs but it requires a local anesthetic agent of short duration with minimal side effects.We compare
the effect of intrathecal chloroprocaine with fentanyl to bupivacaine with fentanyl in ambulatory urology
Materials and Methods: Hundred patients aged 18 – 60 years undergoing ambulatory urology surgery
randomly divided into two groups of 50 each. Group A received 40 mg of 1% chloroprocaine with 20mcg
fentanyl and group B received 7.5 mg of 0.5% bupivacaine and 20mcg fentanyl. Sensory and motor block
characteristics, time to ambulation, void and time for ready to discharge from hospital were recorded.
Results: There was no difference in terms of demographic data and duration of surgery. Peak sensory block
level was T5 in group A and T4 in group B. The mean time to reach the peak block level was similar in
both groups (P=0.228). Time to two-segment regression and regression to the S2 segment were shorter in
group A (P
The length of stay in PACU was similar in both the groups (P=0.729). Time to ambulation, time for first
void and time for ready to discharge from hospital were significantly shorter in group A compared to group
B (P < 0>
Conclusions: Chloroprocaine and fentanyl is a better choice for ambulatory urology surgery in comparison
to low dose bupivacaine and fentanyl.
Keywords: Chloroprocaine, Bupivacaine, Fentanyl, Ambulatory, Urology surgery.