Abstract : Chronic renal failure is a disease characterised by progressive loss of function of kidney over a period of
months and years, and it may lead to one of its recognised complications such as anaemia, cardiovascular
diseases and end stage renal disease. Hemodialysis is a method that is used to achieve the extracorporeal
removal of waste products such as creatinine, urea, free water from blood by an artificial kidney machine,
when the kidneys are in a state of renal failure. The aim of this study was to evaluate and compare serum
urea, creatinine, sodium, potassium chloride levels in chronic renal failure patients before and after dialysis.
The levels of serum urea, creatinine, were found significantly lower in patients after receiving hemodialysis,
while electrolytes came to normal. This study confirms the role of dialysis in prognsis of patients of chronic
Keywords: Biochemical, Dialysis, Extracorporeal.