Abstract : Introduction: Diabetes Mellitus is a group of metabolic disorders characterized by rise in blood glucose
level. The measurement of Glycated Hemoglobin has been widely used to monitor glycemic control in
patients with diabetes mellitus which is also a best marker for monitoring long term complications. As the
prevalence of diabetes is increasing day by day, it is mandatory to give importance for self-management.
Objectives: The objective of the present study was to compare the levels of estimated HbA1c with
calculated HbA1c derived from a simple, cost effective mathematical formula by using fasting plasma
Materials and Methods: The present study comprised of 66 fasting whole blood samples. All the samples
were analyzed for Glycated hemoglobin and glucose, using this blood glucose level HbA1c was calculated
by a formula, HbA1c = 2.6+0.03 + Blood glucose (mg/dl). Both estimated and calculated values of HbA1c
were compared by dependent t-test.
Results: It was observed that the mean + SD levels of Estimated HbA1c and Calculated HbA1c were
7.11+1.89 and 6.60+1.58 respectively. The p value was Conclusion: Therefore the study concluded that, there exists a significant difference between the levels of estimated HbA1c and calculated HbA1c and thus this mathematical formula cannot be used
interchangeably with estimated HbA1c.
Keywords: Glycated hemoglobin (HbA1c), Diabetes mellitus, Fasting plasma glucose.