Abstract : Purpose: The study was conducted to find out the topographic changes of disc, macular thickness, visual
field, and intra-ocular pressure (IOP) after trabeculectomy in different age and sex using Optical Coherence
Tomography (OCT) machine, automated perimeter and Goldman applanation tonometer respectively.
Materials and Methods: It was a prospective, interventional case-series conducted at the glaucoma clinic
at Regional Institute of Ophthalmology, Kolkata from March 2010 to August 2011. Patients of primary
open angle glaucoma who fulfilled the inclusion criteria. The trabeculectomy surgeries were done by a
single surgeon. The disc changes, macular thickness, IOP and visual field changes were measured before
and after trabeculectomy. Preoperative OCT images of disc and macula, visual field testing by Humphrey
automated perimeter and IOP by Goldman applanation tonometry were done/within 3 months prior to
surgery and same investigations had been done postoperatively within 2 to 3 months after surgery. Data
was collected in a standard data collection form and analysis was done by paired t-test.
Results: Significant visual field (mean deviation-MD & pattern standard deviation-PSD in decibel)
changes were seen but the nerve fiber thickness in the disc and macula were not increased. Significant
reduction of IOP was found after trabeculectomy.
Conclusions: Significant visual field (MD& PSD) changes were found after trabeculectomy in early
glaucoma patients but disc and macular changes were found to be insignificant.
Keywords: Automated perimetry, Optical Coherence Tomography, (OCT), Primary open angle glaucoma.