Author : Saurabh Madhav Oza, Renu Mohan Magdum, Varsha V Manade, Madhuri Khandelwal, Namratha Judith Cardoza
Abstract : Purpose: To study the systemic factors (hypertension, dyslipidemia and obesity) affecting diabetic
retinopathy in Type 2 diabetes mellitus and to find out the prevalence of obesity, hypertension and
dyslipidaemia in individuals having diabetes mellitus and association of these comorbidities with diabetic
Materials and Methods: A total of 140 diagnosed diabetic subjects participated in the study. They were
grouped according to the presence or absence of diabetic retinopathy. All the subjects were also evaluated
for hypertension, dyslipidemia and obesity. Observations from both the groups were compared to find
association between the risk factors and retinopathy.
Results: Mean systolic blood pressure among retinopathy subjects(133.13mmHg) was higher than subjects
without retinopathy(127.43mmHg). This difference was found to be statistically significant (p = 0.046).
Mean lipid level among retinopathy subject was not significantly different than the mean lipid levels
in the participants without retinopathy (p > 0.05). The difference between the BMI of the participants
of both groups was found to be insignificant. (p>0.05). Duration of diabetes(p haemoglobin(p= 0.001) were significant factors too.
Conclusion: Duration of diabetes, glycosylated haemoglobin levels, systolic blood pressure were
significant risk factors associated with diabetic retinopathy.
Keywords: Diabetic retinopathy, Dyslipidemia, Glycosylated haemoglobin, Hypertension, Obesity, Systemic factors.