Indian Journal of Microbiology Research

Innovative Education and Scientific Research Foundation

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Registered Under Government of India NGO – Indian Trust Act 1882

Pattern of antibiotic sensitivity among klebsiella isolates from sputum of hospital acquired respiratory tract infection

Article : Open access

Article type : Research Article

Volume : 7

Issue : 1

Year : 2020

Author : Vikas A More, Deepak W Deshkar, Janardhan V Narute, Dhiraj J Trivedi

Page no : 59-62

Abstract : Klebsiella Pneumoniae is one of the most common causes of nosocomial respiratory tract infections all over the world. Unfortunately, it is developing resistance to many antibiotics. This study was carried out in a teaching hospital for determining the prevalence and pattern of antibiotic sensitivity among Klebsiella pneumoniae isolated from sputum samples of hospital acquired respiratory tract infection. Materials and Methods: A total of 154 samples were included in the present study. Klebsiella Pneumoniae were isolated in (21.52%) samples and identified by standard microbiological techniques. Antibiotic susceptibility testing was done by the Kirby-Bauer disc diffusion method and interpreted as per CLSI guidelines. Results: Isolated strains were sensitive to Amikacin (70%) Levofloxacin (70%) Gentamicin (65%) Chloramphenicol (65%) and resistant to Ampicillin (98.72%) Co-trimoxazole (87.5%) Ceftriaxone (85%) Tigecycline (85%) Tobramycin (85%). Conclusion: This study may help to formulate local antibiotic policy as a part of rational antibiotic therapy for hospitals; this may reduce the development of multi-drug resistance. Keywords: Klebsiella Pneumoniae, Sputum, Antibiotic resistance, Antibiotic susceptibility, Nosocomial infection.