Abstract : Background: The placenta is an important structure that supports the pregnancy. The abnormality in the
placental trophoblastic tissues is associated with the various complications during pregnancy. Preeclampsia,
a hypertensive disorder of pregnancy results from the abnormality in the placental trophoblastic tissues and
is the major cause of maternal mortality and morbidity. Several studies have found correlation between
the placental location and development of preeclampsia. Among the various predictors of preeclampsia,
the placental location by ultrasound at 18-24 weeks have been found to be cost effective, non invasive and
associated with good predictive value.
The objective of the study was to assess the relationship between second trimester placental position by
ultrasound and the subsequent development of preeclampsia.
Materials and Methods: A prospective observational study was conducted on 106 singleton pregnant
women from November 2013 to October 2015, attending the antenatal clinic in Sikkim Manipal Institute
of Medical Sciences, Gangtok. The location of placenta was determined by ultrasound at 18-24 week and
patients were followed up till development of preeclampsia or delivery.
Results: Out of 106 patient studied, 69 patient had central placenta and 37 had lateral placenta. A total of 17
patient developed preeclampsia of which 12 had laterally implanted placenta. This finding was statistically
significant with a p value of 0.001.
Conclusion: This study revealed an increased association of development of preeclampsia in patients with
laterally located placenta which aids to preventive approach and optimum management of preeclampsia.
Keywords: Lateral placenta, Preeclampsia, Predictor, Ultrasound.