Indian Journal of Orthopaedics Surgery

Innovative Education and Scientific Research Foundation

Email : editor@iesrf.org
Registered Under Government of India NGO – Indian Trust Act 1882

Multiple spinal neurofibromas with cervical and lumbar cord compression in neurofibromatosis 1 - a rare presentation

Article : Open access

Article type : Case Report

Volume : 6

Issue : 2

Year : 2020

Author : Akshada Sharma, Ratnakar Ambade

Page no : 122-127

Abstract : Neurofibromatosis is a multi system genetic condition with a wide range of neurological manifestations. It is clinically characterized by neurofibromas (benign peripheral nerve sheath tumours), skin involvement, visual complaints along with cardiopulmonary and gastrointestinal complaints. On the basis of affected gene and chromosome, neurofibromatosis may be divided into Type I (Chr. 17) and Type II (Chr. 22). Cervical cord compression due to cervical root neurofibromas represents an important clinical problem in patients with neurofibromatosis type 1 (NF 1), but is rarely reported. 1,2 We report here a rare case, who in addition to classical features of NF-1, had multiple spinal neurofibromas in cervical as well as lumbar spine leading to quadriparesis. Keywords: Neurofibromatosis, Neurofibromatosis type 1, Cervical cord compression, Neurofibroma, Recklinghausen’s disease.