Author : V Rajalakshmi, K Anbukkarasi, Raga Priya D, Hemalatha Ganapathy, Susan D P
Abstract : Introduction: Lichenplanus is a chronic inflammatory disorder with remissions and relapses. The
pathogenesis is likely to be autoimmune, with T Lymphocytes targeting the basal keratinocytes. The clinical
presentation is violaceous papules and plaques in skin, mucous membranes and nails. The aim of this study
is to analyse the clinical and pathological profile of Cutaneous Lichen planus of all patients diagnosed with
Lichen planus attending our hospital from 2016 to 2019.
Materials and Methods: All cases diagnosed as Lichen planus clinically and confirmed
histopathologically are analysed for age, sex, location, duration, associated comorbid conditions, type of
Lichen Planus, histopathological features and for malignant transformation.
Results: Of the 91 patients diagnosed, 83 (91%) were classical Lichen Planus, 6 (6.5%) hypertrophic
Lichen Planus, 2 (2.5%) lichenplanopilaris. The median age was 38 years and the mean age 40 years.
Majority were in the age group of 20 to 40 years. Male : Female ratio was 1.1 :1. 10 (10.98%) patients
were in paediatric age group. 7 (8%) had skin and oral involvement. 40 patients had violaceous plaques &
papules, 46 pigmented and violaceous plaques and papules, 5 hypertrophic pigmented plaques. No nail or
genital involvement was seen in any of our patients.
Conclusion: The predominant type was classical Lichen planus. Few patients had Hypertension, diabetes
Mellitus, diabetes mellitus and hypertension seemed to be age related. No malignant transformation was
Keywords: Llichen planus, Clinical, Histopathology, Malignant transformation.