Abstract : Traditional system of medicines has been in use since ages throughout the world. Ayurvedic granthokt extracts have been in use to treat many disorders which are either non-communicable or lifestyle oriented or due to stress. Rheumatoid arthritis is one of the autoimmune disorder which might arise due to faulty metabolism of body or stress. It is a chronic inflammatory disorder which results in severe pain, discomfort and sometimes disability in the patients. Modern medicines aims to reduce pain but the root cause remains unattended. Hence the main objective was to assess the in vitro Antioxidant and Anti-inflammatory activity of the Ayurvedic formulation Maharasnadi kwath extract and Stifain tablet. The Antioxidant properties of the Maharasnadi kwath and Stifain tablet were evaluated by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay. Anti-inflammatory activity was estimated by inhibition of protein denaturation method. The aqueous extract of Maharasnadi and Stifain tablet showed good anti-inflammatory activities and potent antioxidant capacity.
Keywords: Antioxidant, Anti-inflammatory activity, Albumin denaturation, Maharasnadi kwath, Stifain tablet, Nervous system.